Pharmaceutical Name: Aldactone 25 (Pfizer)
Chemical name: Spironolactone
Chem. Abstr. Name: 17-hydroxy-7α-mercapto-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone acetate
Molecular Weight: 416.574 gr/mol
Aldactone is an aldosterone antagonist. Aldactone influences the body’s own hormone, aldosterone, which accelerates the excretion of potassium and reduces the excretion of sodium and water. Aldosterone regulates the endogenous water household. The higher the aldosterone level, the more water is stored in the body. The use of Aldactone, results in a significant reduction in the aldosterone level so that an increased excretion of sodium and water occurs while, at the same time, potassium is reabsorbed. This also explains why Aldactone is called a potassium-sparing diuretic since it does not cause a loss of potassium like thiazides and furosemides. Users must strictly observe that during the use of Aldactone no additional potassium is taken since this would cause a life-threatening increase in the serum potassium level. Potassium sparing diuretics have relatively low diuretic effects so that Aldactone can be called a mild diuretic. It is interesting to note that Aldactone is also an anti-androgen since it reduces the androgen level. Female athletes take advantage of this characteristic by using Aldactone to minimize the virilization symptoms during steroid treatment or the symptoms after treatment. For this purpose Aldactone is normally taken daily for 10 to 14 days, usually in a dose of 50 mg/day. Bodybuilders use Aldactone almost exclusively during the last week before a competition. Since this causes neither a dramatic nor an immediately noticeable draining effect, Aldactone is usually taken over 5-6 days in a dosage of 2 tablets of 50 mg daily. Aldactone should not be used to expediently drain water at the last minute. Both male and female athletes may take Aldactone. The side effects of potassium-saving diuretics, like Aldactone, are relatively low compared to thiazides and furosemide.
Each box contains 20 pills with 25 mg/each
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