Ipamorelin is a
fascinating new muscle building discovery that is getting a lot of attention in
the bodybuilding world. Like the GHRP-6 peptide (growth hormone releasing
hexapeptide), it is a synthetic peptide that has powerful Growth Hormone
releasing properties. And these GH releasing properties are what is of interest
to athletes and bodybuilders since they can make a tremendous difference in the
amount of muscle you can grow and how quickly you burn fat.
Athletes are taking Ipamorelin in a 200 mcg -300
mcg dosage, two or three times daily, using a tiny insulin needle to inject.
They usually start with the lower dose since side effects can include headaches
or what feels like a head-rush. Ipamorelin can be taken at anytime but taking
it about 30-45 minutes before a workout would seem ideal because of the pulse
in Growth Hormone (GH) it creates allowing for maximum growth.
Studies on the effects of Ipamorelin on bone
growth, body weight, and GH release showed some interesting conclusions.
In one experiment, various doses were administered
over the course of 15 days to test the group's reactions.
There was a distinct and dose-dependent effect on
body weight gain however, the treatment group did not show a change in total
IGF-I levels. Nor did the treatment group produce serum markers of bone
development. For example, the number of cells in the wide portion of the tibia
(the shinbone) did not change significantly. This is a good thing because it suggests
muscle growth with less potential for deformity of bone or cartilage.
The reaction of the pituitary to an aggressive
i.v. dose of Ipamorelin showed that plasma GH levels were notably reduced
whereas they were unchanged after a comparable dose of GHRH. This is actually a
good thing as it suggests that Ipamorelin may not decrease your body's natural
GH production - further demonstrating that Ipamorelin is a selective GH
releaser.
