Growth Hormone Releasing Peptide-2 (GHRP-2), also known as Pralmorelin,
is a synthetically made growth hormone secretagogue, a peptide that stimulates
the body to increase natural production of growth hormone. GHRP-2 is an agonist of ghrelin, a gut peptide
and also known as “the hunger hormone”, which binds to the growth hormone
secretagogue receptor. Ghrelin has been shown to stimulate growth hormone
secretion and appetite initiation.
Usage
GHRP-2 is used to increase muscle mass, decrease
body fat, and enhance flexibility and joint health. GHRP-2 also promotes better
recovery from injuries and training. GHRP-2 is also functions to improve sleep,
enhance anti-aging benefits, and improved overall health and wellness. Higher
growth hormone levels also lead to greater production of IGF-1 in the body,
which improves in lean body composition, accelerates growth of muscle tissue
and reduces body fat. GHRP-2 promotes significant increase in strength and
endurance, especially when used long term. Athletic performance, physical
capacity, and aging-related decline all have the ability to improve drastically
with the use of this peptide.
GHRP-2 is widely regarded as one of the most
effective growth hormone releasing peptides for both athletic performance and
anti-aging effects. It promotes substantial increases in the body’s output of
growth hormone while minimizing the powerful hunger side effects associated
with GHRP-6. This may lead to significant improvements in lean body composition.
Mechanism of Action
GHRP-2 works to enhance natural growth hormone
production in two ways. First, the GHRP-2 intensifies the natural growth
hormone releasing signal, resulting in a substantial secretion of growth
hormone. Second, it suppresses a hormone in the body called somatostatin, also
known as growth hormone inhibiting hormone (GHIH). Somatostatin generates the
body to decrease its natural growth hormone production. By restricting the
activity of somatostatin, GHRP-2 can improve growth hormone creation, resulting
in increased natural growth hormone levels. GHRP-2 also activates ghrelin, a
peptide hormone produced in the gastrointestinal system, which has strong
effects on growth hormone production and appetite.
As GHRP-2 stimulates the body to create growth
hormone, there is no shutdown of natural growth hormone production as occurs
with synthetic hGH administration. GHRP-2 causes growth hormone secretion in a
manner that firmly resembles natural release patterns, instead of being
continually raised. This method prevents many of the negative side effects of
synthetic hGH administration, including the shutdown of natural growth hormone
production.
Administration
Mode of Administration: Subcutaneous injection to
a fleshy part of the body, typically to the stomach or abdominal area. GHRP-2
can also be taken orally and intranasal.
Before administering GHRP-2, always be sure to use
a clean and sterile syringe.
Hold the GHRP-2 vial upright and insert the syringe
in the center of the cap.
Draw the plunger until you have the correct amount
(see ‘Dosage’ below) in the syringe and carefully remove it.
Before administering the syringe, use alcohol to
cleanse the area of skin.
Pinch the skin around the area to be injected,
leave about 2 cm on each side.
Hold the syringe at a 90 degree angle to your skin
and swiftly insert the syringe.
Depress the plunger fully, until the syringe is
empty, and carefully draw out.
Dosage
Dosage Amount:150mcg -300mcg (0.15mg - 0.3mg)
Dosage Frequency:1 to 3 times daily
GHRP-2 is generally administered 1-3 times daily
at dosages ranging from 150mcg to 300mcg per administration.
For strength gain or performance enhancement:
Recommended dosage of 300mcg (0.3mg) administered 3 times a day.
For anti-aging purposes: Recommended dosage of
150mcg (0.15 mg) prior to bed once daily.
For best results, it is recommended to avoid
eating at least 1 hour before and after administering GHRP-2.
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