Selank 10Mg

Selank is small and only a fraction of the size of most naturally-occurring proteins. It was developed at the Institute of Molecular Genetics (Russian Academy of Sciences) in cooperation with the V.V. Zakusov Research Institute of Pharmacology (Russian Academy of Medical Sciences), along with its “cousin” drug, Semax.

Selank was derived by combining the sequence of a peptide called tuftsin with another sequence that improves its molecular stability. Tuftsin is naturally-occurring, and makes up one part of the natural antibody IgG.

Both tuftsin and Selank have been reported to reduce anxiety and increased serotonin levels in rats, with Selank being slightly more effective.

Selank has been approved in Russia for the treatment of generalized anxiety disorder (GAD) and for its use as a nootropic. However, the FDA has not approved its use for any conditions. Nonetheless, Selank continues to be available in several countries, where it is often sold as a “nutritional supplement.”

Selank Mechanism of Action

Although the mechanisms behind Selank are not yet fully known for certain, Selank is believed to act in part by stabilizing enkephalins in the blood. Enkephalins are natural peptides in the body that are believed to counteract the stress response.

However, one animal study in mice did not demonstrate the stabilization of enkephalins following dosing with Selank, and the treated mice also did not appear to benefit from any significant “anti-anxiety” effects.

According to some cell studies, Selank may bind to GABA receptors. By extensions, most compounds that bind to GABA receptors generally cause “sedative” effects. In one study of mice treated with Selank, researchers reported increased activity in inhibitory neurons, which rely on GABA. This resulted in less overall brain activity, which is generally consistent with a sedative effect.

In addition, some researchers have reported an increase in BDNF, an important brain-growth compound (neurotropic factor) which has been implicated in learning and memory. Some researchers have suggested that this mechanism may be responsible for some of Selank’s claimed cognitive effects.

Selank has also been reported to influence the levels of the neurotransmitters norepinephrine, dopamine, and serotonin in mice. These neurotransmitters are widely believed to be involved in motivation, focus, and pleasure.

Selank 10Mg by Beligas pharmaceuticals + Water